DENTAL CARIES IN THE COTTON EAT(23)

imental animals. The results of the presentstudy confirm those of Zepplin et al. and further support theobservation made previously (Constant et al., '51) that undercertain conditions complex carbohydrates may be as cario-genic as simple sugars.Work in this laboratory has shown that the physical stateof the diet (Anderson et al., '48; Smith, '48; Constant et al.,'51), and the ratio of cariogenic to anti-cariogenic nutrients(Schweigert et al., '46; Constant, '51), as well as the totalamount of carbohydrate or fermentable sugar, may alter theextent of caries production. The protein, carbohydrate, andfat levels of the natural and the 67% sucrose diets employedwere similar. Smith ('48) found that dextrin in the form ofa fine flour resulted in approximately twice as many cariousfissures as less