〔摘要〕 目的:观察碘复冲洗消毒感染根管的抗菌效果。方法:共收集35例感染根管标本,实验组20例用0.5 g/L碘复冲洗根管然后封5 g/L碘复原液,对照组15例用过氧化氢液和生理盐水冲洗根管,封FC于根管,分别在用药前后进行细菌标本采样、培养、分离与鉴定,观察CFU变化及细菌检出情况。结果:使用0.5 g/L碘复冲洗根管的抗菌作用明显优于临床用H2O2和生理盐水联合冲洗的效果;用5 g/L碘复封药消毒根管的杀菌作用与FC相当。结论:碘复对感染根管内厌氧菌有良好的抗菌效果。
Antibacterial activity of iodophors in the irrigation and
disinfection of infected root canal
Tang Zisheng,Yin Shihai,Ba Xiu.Shan
ghai Yangpu Antu Hospital,Shanghai 20093
〔Abstract〕Objective: To evaluate the antibacterial effects of iodophors on infected root canal.Methods:35 infected root canals(in the teeth with single canal) were collected from clinical patients.In experimental group,0.5 g/L and 5 g/L iodophors were used as irrigate agent and disinfectant,respectively,while in the control group 3%H2O2+9 g/L N S and FC were used.The difference of CFU before and after the treatment was caculated,as well as the bacterial accidence.Results:The antibacterial effect of 0.5 g/L iodophors was stronger than that of H2O2 and saline in irrigation (P<0.05).There was no significant difference betwen 5 g/L iodophors and FC in disinfection (P>0.05).Conclusion:Iodophors can be used as irrigate agent and disinfectant for the treatment of infected root canal.
Key words Iodophors;Root canal irrigants; Disinfection;Periapical periodontitis
碘复是碘与表面活性剂的结合产物,具有高效、迅速、广谱抗菌作用,而对人体无毒、无刺激性〔1〕,是近年来国内外临床上颇受重视的消毒药物。据研究报道,碘复在体外对从口腔分离出来的厌氧菌具有很强的杀灭效果〔2〕。为评价碘复在人体感染