【摘要】 目的 对先天性腭咽闭合功能不全（congenital velopharyngeal insuffence,CVPI）定量研究。方法 应用气流、气压测定仪对27例CVPI患者测量口腔压力、鼻腔气流及腭咽闭合 面积， 比较CVPI患者在发hemper和papa音时与正常语音者之间的变化值。结果 CVPI和正常语音两组间在口腔压力和腭咽闭合面积差异无显著性，但两组间的鼻腔气流量差异有显著性（P＜0.07）。结论 诊断CVPI仅用传统的0.20 cm2这一标准不能真实反映腭咽闭合功能，CVPI患者的鼻腔气流量明显高于对照组。
Study of congenital velopharyngeal insufficiency and hypernasality
WANG Guomin，YUAN Wenhua，JIANG Liping（Cranilfa
cial Center, School of Stomatology, Shanghai Second Medical University,Shanghai 200011, China）
【Abstract】 Objective to evaluate 27 congenital veloparyngeal insufficiency(CVPI) subjects and 6 normal articulation subjects with airflow pressure techniques. Methods A compare analysis was performed in two groups (CVPI subjects and normal articulation subjects) during speech production of /hemper/ and /papa/. Results there wasn't statistical significance between two groups in oral air pressure and velopharyngeal orifice areas, however, CVPI group differed significanth in nasal airflow on the articulation of/hemper/ and /papa/. Conclusions When the degree of CVPI subject's VP opening was small, hypernasality appeared to be related to duration of the opening-closing movements.
【Key words】 Velopharyngeal insufficiency; Voice; Nasal airflow
先天性腭咽闭合功能不全(congenital velophar-yngeal insuffency, CVPI)是一种严重影响生活质量和有待进一步认识的先天性疾患。其主要临床症状是以严重过度鼻音为主的语音障碍。由于CVPI患者的口腔和颌面部无明显的解剖异常（可伴粘膜下隐裂或悬雍垂裂），常常延误了最佳治疗时机。
近年来，临床
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