摘要 目的:研究颞下颌关节骨关节病(TMJOA)对关节盘的影响。方法:选择健康成年无角努比羊12只,随机分为对照组(2只)和实验组(10只),关节上腔内注射1%胶原酶建立TMJOA动物模型,分别于实验后1、2、3、4、6月处死山羊,结合组织病理学改变,观测病变关节盘位置改变情况。结果:在OA病变基础上存在肯定的关节盘位置改变。结论:本实验条件下,颞下颌关节盘移位可能是OA病变发展到一定阶段时的继发改变。
A Dynamic Study of Influences of TMJOA on TMJ Disc
Chen Gang, Hu Bo, Wang Dazhang, et al
College of Stomatology, West China University of Medical Sciences
Abstract Objective:To learn the changes of TMJ disc positions under the influences of TMJ Osteoarthrosis(TMJOA). Methods: The TMJOA experimental animal model was established by12 goats. The TMJ disc positions were observed and recorded at different intervals, (1 month, 2 months, 3 months, 4 months and 6 months) then the pathological changes of TMJ specimens were also studied.Results: Significant anteromedial shift of TMJ disc position was observed in some certain TMJOA phases and became more obviously along with the disease progress.Conclusion: The shift of TMJ disc may be the secondary change of TMJOA.
Key words: temporomandibular joint internal derangement osteoarthrosis animal model anterior shift of TMJ disc
颞下颌关节内紊乱症(temporomandibular joint internal derangement, TMJID)是指关节盘、髁状突、关节结节和关节凹之间,主要是关节盘与髁状突之间的三维空间位置关系异常,形成关节内局限的、妨碍关节平滑运动的机械性结构紊乱,从而引起的以颞下颌关节(TMJ)区疼痛、异常关节音及下颌功能运动障碍为主要特征的一组病征［1～3］。颞下颌关节骨关节病(temporomandibular joint osteoarthrosis, TMJOA)是以滑膜关节软骨组织面的破坏与耗损为主要特征并伴发软骨下骨组织改建和滑膜相应改变的关节疾病［3～6］。有学者认为,以关节盘前移位(anterial disc displacement, ADD)为基本特征的TMJID是TMJOA发展过程的一种伴发病损,但临床发现
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